Brighton & Hove Albion vs Tottenham Hotspur: Predictions, Odds, Lineups, Preview

• Brighton are pricked to get back to winning ways with a home win, this time against Tottenham Hotspur.

• Thomas Frank's side won 3-0 last time out against West Ham, but Ladbrokes is tipping Brighton to get the better of them on September 20.

• Kaoru Mitoma is the main to watch for Brighton, and he could be the difference maker for the Seagulls against Spurs this weekend.

Explore Ladbrokes’ detailed preview for Brighton & Hove Albion vs Tottenham Hotspur in the Premier League. Stats, odds, predictions, and lineups for the 15:00 BST match.

• Fixture: Brighton & Hove Albion vs Tottenham Hotspur

• Date: Saturday, 20 September 2025

• Kick-off: 15:00 BST

• Venue: American Express Stadium

Match Prediction: Brighton & Hove Albion 2-1 Tottenham Hotspur

Brighton's up-and-down form could make this a tricky one. They've shown they can beat the big guns at home, like when they nicked a 2-1 win over Manchester City. But away losses to Bournemouth and Everton might make them a bit cagey. Still, with players like Mitoma and Welbeck, they've got the firepower to cause Spurs problems.

Tottenham, on the other hand, have been on a bit of a roll lately. Three wins in their last four league games, including a thumping of West Ham, show they're in good nick. That loss to Bournemouth at home was a blip, but they bounced back strong last time out in the English top-flight. If they keep their heads, they could nick this one on the road.

Brighton's recent form has been a bit of a rollercoaster. That win over Manchester City at home was a real statement, showing they can mix it with the best. But those losses to Bournemouth and Everton away from home suggest they struggle on the road. They'll need to be on it from the off if they want to get anything from this game against a dangerous Spurs side.

Recent Premier League Results:

• Loss: 1-2 vs AFC Bournemouth (A)

• Win: 2-1 vs Manchester City (H)

• Loss: 0-2 vs Everton (A)

• Draw: 1-1 vs Fulham (H)

Spurs have been in decent form, winning three of their last four Premier League matches. That 3-0 win over West Ham was a real confidence booster, and they came up with another solid performance before that against Manchester City. The only hiccup was the home loss to Bournemouth, but they've bounced back well. If they can keep that momentum going, they'll be tough to beat.

Recent Premier League Results:

• Win: 3-0 vs West Ham United (A)

• Loss: 0-1 vs AFC Bournemouth (H)

• Win: 2-0 vs Manchester City (A)

• Win: 3-0 vs Burnley (H)

Brighton have had the slight upper hand recently, winning three of the last five meetings, although Tottenham won the other two games in the five-game run. Brighton have scored plenty of goals against Tottenham, so Spurs will need to be on their toes.

Recent Premier League Results

• Tottenham Hotspur 1-4 Brighton & Hove Albion (25 May 2025)

• Brighton & Hove Albion 3-2 Tottenham Hotspur (06 Oct 2024)

• Tottenham Hotspur 2-1 Brighton & Hove Albion (10 Feb 2024)

• Brighton & Hove Albion 4-2 Tottenham Hotspur (28 Dec 2023)

• Tottenham Hotspur 2-1 Brighton & Hove Albion (08 Apr 2023)

• Adam Webster  (Cruciate Ligament) - Out

• Jack Hinshelwood (Ankle) - Doubt

• Maxim de Cuyper (Knee) - Doubt

• Solly March (Knee) - Out

• Mats Wieffer (Knee) - Doubt

• Dejan Kulusevski  (Knee) - Out

• James Maddison (Cruciate Ligament) - Out

• Kota Takai (Foot) - Out

• Radu Drăgușin (Cruciate Ligament) - Out

• Dane Scarlett (Groin) - Doubt

• Dominic Solanke (Ankle) - Doubt

• Yves Bissouma  (Knock) - Doubt

• Verbruggen, Veltman, Hecke, Dunk, Kadioglu, Milner, Ayari, Minteh, Rutter, Mitoma, Welbeck

With Dunk and Hecke at the back, Brighton will look to keep things tight. Mitoma and Welbeck up top will be key to breaking down Tottenham's defence.

• Vicario, Porro, Romero, Van de Ven, Spence, Sarr, Palhinha, Bergvall, Kudus, Tel, Simons

Spurs will rely on Romero and Van de Ven to keep things solid at the back. In attack, Simons and Kudus will be crucial in creating chances.

• Lewis Dunk vs Mathys Tel: A battle that could decide whether Brighton can keep a clean sheet.

• Kaoru Mitoma vs Pedro Porro: Mitoma's pace against Porro's defensive nous will be a key duel.

• Lewis Dunk (Brighton & Hove Albion): The captain will need to lead by example at the back.

• Xavi Simons (Tottenham Hotspur): His creativity could unlock Brighton's defence.

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Odds and market details are accurate as of the time of publication.