Chelsea vs Barcelona: Predictions, Betting odds, Lineups, Preview

Explore Ladbrokes' detailed preview for Chelsea vs Barcelona in the UEFA Champions League. Stats, odds, predictions, and lineups for the 20:00 GMT match.

• Fixture: Chelsea vs Barcelona
• Date: Tuesday, 25 November 2025
• Kick-off: 20:00 GMT
• Venue: Stamford Bridge

Chelsea's recent form suggests they're in a good place, with two wins and a draw in their last four matches. Their home victories against Ajax and Benfica show they can dominate when playing at Stamford Bridge, and their draw against Qarabag indicates resilience. Expect Chelsea to press high and exploit their attacking options, particularly with players like Garnacho and Pedro leading the charge. However, their loss to Bayern München away from home shows they can be vulnerable against top teams, so they'll need to be on their toes against Barcelona.

Barcelona, on the other hand, have had a mixed bag of results, with two wins, a draw, and a loss in their recent outings. Their convincing win against Olympiakos at home and the victory over Newcastle away show they can be formidable, but the draw against Club Brugge and the loss to PSG at home suggest inconsistency. Barcelona will likely look to control possession and use their attacking flair, with players like Yamal and Raphinha posing threats. This match could be a tight affair, with both teams looking to assert dominance but potentially settling for a draw.

Chelsea's recent form has been solid, with two wins, a draw, and a loss in their last four games. Their home victories against Ajax and Benfica demonstrate their strength at Stamford Bridge, where they'll be playing Barcelona. The draw against Qarabag shows they can hold their own even when not at their best.

However, the loss to Bayern München away from home is a reminder that they need to be at their best against top-tier opposition like Barcelona.

Recent UEFA Champions League Results:

• Draw: 2-2 vs Qarabag (A)

• Win: 5-1 vs Ajax (H)

• Win: 1-0 vs Benfica (H)

• Loss: 1-3 vs Bayern München (A)

Barcelona's recent performances have been a bit of a rollercoaster, with two wins, a draw, and a loss in their last four matches. Their home win against Olympiakos and the away victory over Newcastle highlight their potential to dominate. However, the draw against Club Brugge and the home loss to PSG indicate they can be inconsistent. Barcelona will need to find their rhythm and capitalise on their attacking prowess to challenge Chelsea at Stamford Bridge.

Recent UEFA Champions League Results:

• Draw: 3-3 vs Club Brugge KV (A)
• Win: 6-1 vs Olympiakos Piraeus (H)
• Loss: 1-2 vs Paris Saint Germain (H)
• Win: 2-1 vs Newcastle (A)

The head-to-head record between Chelsea and Barcelona shows a competitive history, with Barcelona winning 3-0 in their most recent encounter in 2018. The teams have also played out a 1-1 draw and two 2-2 draws in previous meetings. This suggests that matches between these two teams are often closely contested, with both sides capable of scoring and defending well.

Recent UEFA Champions League Results

• Barcelona 3-0 Chelsea (14 Mar 2018)

• Chelsea 1-1 Barcelona (20 Feb 2018)

• Barcelona 2-2 Chelsea (24 Apr 2012)

• Chelsea 1-0 Barcelona (18 Apr 2012)

• Levi Colwill (Knee) - Out

• Cole Palmer (Toe) - Out

• Benoît Badiashile (Muscle) - Out

• Mykhailo Mudryk (Suspended) - Out

• Roméo Lavia (Thigh) - Out

• Dário Essugo (Surgery) - Doubt

• Pedro Neto (Groin) - Doubt

• Enzo Fernández (Knee) - Doubt

• Pedri (Muscle) - Out

• Gavi (Knee) - Out

• Marc-Andre ter Stegen (Back) - Doubt

• Andreas Christensen (Muscle) - Doubt

• Predicted lineup: Sanchez (GK), James (DF), Adarabioyo (DF), Hato (DF), Cucurella (DF), Santos (MF), Caicedo (MF), Estêvão (MF), Pedro (MF), Garnacho (MF), Delap (AT)

Chelsea's predicted lineup suggests a focus on attacking play, with Delap and Joao Pedro leading the front line. The midfield duo of Santos and Caicedo will need to control the tempo of the game and provide support to the forwards.

• Predicted lineup: Szczesny (GK), Garcia (DF), Araujo (DF), Cubarsi (DF), Balde (DF), Casado (MF), De Jong (MF), Yamal (MF), Fermin (MF), Raphinha (MF), Torres (AT)

Barcelona's predicted lineup indicates a reliance on their attacking talent, with Yamal, Raphinha, and Torres up front. The midfield duo of Casado and De Jong will be crucial in maintaining possession and feeding the forwards.

• Garnacho vs Garcia: This will be a key battle between Chelsea's dynamic attacker and Barcelona's solid defender.

• Santos vs Lopez: This midfield duel will be crucial, with Chelsea's Andrey Santos looking to control the game against Barcelona's Fermin Lopez.

• Pedro (Chelsea): Pedro's pace and finishing make him a vital part of Chelsea's attacking threat.

• Yamal (Barcelona): Yamal's creativity and flair on the ball make him a key player for Barcelona's attack.

Chelsea vs Barcelona at 20:00 GMT on Tuesday, 25 November 2025, will be broadcast live for viewers in the UK on Amazon Prime Video.

Ladbrokes is predicting that the score will be Chelsea 2-2 Barcelona in this match.

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For the best UEFA Champions League outright predictions, explore our guide.

Odds and market details are accurate as of the time of publication.