Liverpool vs Everton: Predictions, Odds, Lineups, Preview

• Liverpool are predicted to make it five wins out of a possible five with a Merseyside Derby victory.

• However, despite keeping back-to-back clean sheets, Everton are still expected to score at Anfield.

• Alexander Isak make his Liverpool debut, either from the start or off the bench, and will be eager to find the back of the net.

Explore Ladbrokes’ detailed preview for Liverpool vs Everton in the Premier League. Stats, odds, predictions, and lineups for the 12:30 BST match.

• Fixture: Liverpool vs Everton

• Date: Saturday, 20 September 2025

• Kick-off: 12:30 BST

• Venue: Anfield

Match Prediction: Liverpool 2-1 Everton

Liverpool's recent form has been nothing short of sensational, with four straight league wins, including tight victories against Burnley and Arsenal. They've shown they can grind out results and also put on a show, like in their 4-2 thrashing of Bournemouth. 

Expect them to dominate possession and create numerous chances, but Everton won't make it easy for them. The Toffees have been solid at the back and can nick a goal on the break, which could make for a nervy finish.

Everton have been inconsistent, with two wins, a draw and a loss in their last four league outings. They've shown they can compete, like in their win against Wolves, but consistency is their Achilles' heel. 

They'll likely sit deep and look to hit Liverpool on the counter, but they'll need to be clinical if they want to get anything from this game. It's going to be a tough ask, but they've got the players to cause an upset.

Liverpool are in red-hot form, winning their last four league games, including a gritty 1-0 win against Arsenal at home. They've shown they can win in different ways, from tight games to high-scoring thrillers. 

This confidence and versatility will be crucial against Everton, who can be stubborn at the back. Expect Liverpool to come out firing on all cylinders, looking to continue their winning streak.

Recent Premier League Results:

• Win: 1-0 vs Burnley (A)

• Win: 1-0 vs Arsenal (H)

• Win: 3-2 vs Newcastle United (A)

• Win: 4-2 vs AFC Bournemouth (H)

Everton have had a mixed bag of results recently, with a draw against Aston Villa, wins over Brighton and Wolves and a loss to Leeds. They've shown they can compete, as evidenced by their win against Wolves, but struggle to string together consistent performances. 

This inconsistency could be their downfall against a rampant Liverpool side. They'll need to be at their best defensively and take any chances they get if they want to pull off a surprise.

Recent Premier League Results:

• Draw: 0-0 vs Aston Villa (H)

• Win: 3-2 vs Wolverhampton Wanderers (A)

• Win: 2-0 vs Brighton & Hove Albion (H)

• Loss: 0-1 vs Leeds United (A)

Liverpool has had the upper hand in recent meetings, winning three of the last five encounters, including a 1-0 victory in their most recent clash. Everton managed a draw and a win in that period, but Liverpool's dominance is clear.

Recent Premier League Results

• Liverpool 1-0 Everton (02 Apr 2025)

• Everton 2-2 Liverpool (12 Feb 2025)

• Everton 2-0 Liverpool (24 Apr 2024)

• Liverpool 2-0 Everton (21 Oct 2023)

• Liverpool 2-0 Everton (13 Feb 2023)

• Stefan Bajcetic (Hamstring) - Doubt

• Curtis Jones (Knock) - Doubt

• Jarrad Branthwaite (Hamstring) - Out

• Vitaliy Mykolenko (Muscle) - Doubt

• Alisson, Szoboszlai, Van Dijk, Konaté, Kerkez, Gravenberch, Mac Allister, Salah, Wirtz, Gakpo, Ekitiké

With a strong backline of Van Dijk and Konaté, Liverpool should be solid at the back. In attack, Salah and Gakpo will look to exploit any gaps in Everton's defence with their pace and finishing.

• Pickford, O’Brien, Keane, Tarkowski, Garner, Gueye, Iroegbunam, Ndiaye, Dewsbury-Hall, Grealish, Beto

Everton will rely on the experience of Pickford in goal and the defensive partnership of Keane and Tarkowski to keep Liverpool at bay. Grealish and Dewsbury-Hall will be key in midfield, looking to break up play and launch quick counters.

• Salah vs Garner: Salah's pace and finishing will be tested by Garner’s defensive nous.

• Szoboszlai vs Grealish: Grealish’s movement and dribbling skills will look to exploit any weaknesses in Szoboszlai’s defending.

• Szoboszlai (Liverpool): His creativity and vision, even from the right-back position, will be crucial in breaking down Everton's defence.

• Grealish (Everton): His experience and ability to control the tempo will be vital for Everton's chances of pulling off an upset.

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Odds and market details are accurate as of the time of publication.