Monaco vs Tottenham Hotspur: Predictions, Betting odds, Lineups, Preview

Explore Ladbrokes' detailed preview for Monaco vs Tottenham Hotspur in the Champions League. Stats, odds, predictions, and lineups for the 20:00 BST match.
Match Details
- Fixture: Monaco vs Tottenham Hotspur
- Date: Wednesday, 22 October 2025
- Kick-off: 20:00 BST
- Venue: Stade Louis II.
Our predictions for Monaco vs Tottenham Hotspur
Match Prediction: Monaco 2-1 Tottenham Hotspur
Monaco's recent form has been a bit of a rollercoaster, drawing with Manchester City at home but then getting hammered by Club Brugge away. They'll be looking to bounce back with a strong performance against Tottenham. With players like Balogun and Fati up front, they've got the firepower to cause problems, but they'll need to tighten up at the back after that Brugge defeat.
Tottenham, on the other hand, have shown they can grind out results, drawing away at Bodø / Glimt and then nicking a win against Villarreal at home. They'll fancy their chances of getting something from this game, especially with Bentancur pulling the strings in midfield. It could be a tight affair, but Spurs have the resilience to keep it close.
Form Guide & Team Overview
Monaco
Monaco's recent results have been a mixed bag. They managed a solid draw against Manchester City at home, showing they can compete with the big boys. However, that heavy loss to Club Brugge away will be a concern. They'll need to be more solid defensively if they want to get a result against Tottenham.
Recent Champions League results:
- Draw: 2-2 vs Manchester City (H)
- Loss: 1-4 vs Club Brugge (A)
Tottenham Hotspur
Tottenham have been steady rather than spectacular lately. That draw away at Bodø / Glimt was a decent result, and they preceded it with a professional win against Villarreal at home. They'll be confident they can get something from this game, especially with their strong midfield trio of Bergvall, Sarr, and Bentancur.
Recent Champions League results:
Draw: 2-2 vs Bodø / Glimt (A)
Win: 1-0 vs Villarreal (H)
Head-to-Head Record
Monaco and Tottenham have met twice before, with Monaco coming out on top both times. In November 2016, Monaco beat Tottenham 2-1 at home, while in September 2016, they won 2-1 away. Monaco will be looking to continue their winning streak against Tottenham in this match.
Recent Champions League results:
- Monaco 2-1 Tottenham Hotspur (22 Nov 2016)
- Tottenham Hotspur 1-2 Monaco (14 Sep 2016)
Team News & Injury Report
Monaco
Lucas Michal (International Duty) - Out
Lamine Camara (Ankle) - Out
Denis Zakaria (Adductor) - Out
Eric Dier (Hamstring) - Out
Lukas Hradecky (Knee) - Doubt
Christian Mawissa (Hamstring) - Doubt
Paul Pogba (Thigh) - Doubt
Vanderson (Hamstring) - Doubt
Tottenham Hotspur
James Maddison (Cruciate Ligament) - Out
Radu Drăgușin - (Cruciate Ligament) - Out
Kota Takai (Foot) - Doubt
Dane Scarlett (Groin) - Doubt
Randal Kolo Muani (Muscle) - Doubt
Yves Bissouma (Knee) - Doubt
Dominic Solanke (Ankle) - Doubt
Destiny Udogie (Discomfort) - Doubt
Mathys Tel (Calf) - Doubt
Christian Romero (Muscle) - Doubt
Ben Davies (Muscle) - Doubt
Dejan Kulusevski (Knee) - Doubt
Lineups & Tactical Setup
Monaco (4-3-2-1)
Predicted lineup: Köhn (GK), Diatta (DF), Kehrer (DF), Salisu (DF), Quattara (DF), Teze (MF), Coulibaly (MF), Minomino (MF), Fati (AT), Akliouche (AT), Balogun (AT)
With Kehrer and Salisu at the back, Monaco will look to be more solid defensively after that Brugge defeat. Up front, Balogun and Fati will be key to unlocking Tottenham's defence.
Tottenham Hotspur (4-3-3)
Predicted lineup: Vicario (GK), Porro (DF), Van de Ven (DF), Danso (DF), Spence (DF), Sarr (MF), Bentancur (MF), Bergvall (MF), Simons (AT), Richarlison (AT), Kudus (AT)
Tottenham's midfield of Bergvall, Sarr, and Bentancur will be crucial in controlling the game. Up top, Richarlison and Kudus will look to exploit any gaps in Monaco's defence.
Key Battles & Players to Watch
Folarin Balogun vs Micky Van de Ven: This will be a key battle between Monaco's sharp striker and Tottenham's solid defender.
Takumi Minamino vs Rodrigo Bentancur: Watch out for the duel between Monaco's versatile midfielder and Tottenham's experienced playmaker.
Mamadou Coulibaly (Monaco): Coulibaly's energy and work rate in midfield will be vital for Monaco's performance.
Mohammed Kudus (Tottenham Hotspur): His pace and directness up front could cause problems for Monaco's defence.
FAQs
How to watch Monaco vs Tottenham Hotspur
Fans in the UK are able to watch Monaco vs Tottenham Hotspur on TNT Sports 3 at 20:00 BST on Wednesday, 22 October 2025
What is Ladbrokes' prediction for Monaco vs Tottenham Hotspur?
Ladbrokes is predicting that the score will be Monaco 2-1 Tottenham Hotspur in this match
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