Southampton vs Manchester City: Betting odds, Lineups, Predictions, Preview

Explore our detailed preview for Southampton vs Man City in the Premier League. Stats, odds, predictions, and lineups for the 15:00 BST match.

Fixture: Southampton vs Man City
Date: Saturday 10 May 2025
Kick-off: 15:00 BST
Venue: St. Mary's Stadium

This match is likely to see Manchester City dominate possession and create numerous scoring opportunities. Southampton, already relegated, will look to frustrate City and possibly catch them on the counter. However, City's quality and depth should see them through, even with several key players sidelined.

It's difficult to see Southampton creating too many clear-cut chances, let alone putting one of them away, so we're expecting City to ease home to a comfortable away win, keeping a clean sheet.

Match Prediction: Southampton 0-3 Manchester City

Southampton's recent form has been challenging, with the team struggling to find consistency.

The Saints are currently bottom of the Premier League table, having been relegated to the Championship already. Interim manager Simon Rusk will be looking to end the campaign on a positive note, despite the team's struggles.

Last 5 league matches:

• Loss: 0-2 vs Leicester (A)
• Loss: 1-2 vs Fulham (H)
• Draw: 1-1 vs West Ham (A)
• Loss: 0-3 vs Aston Villa (H)
• Loss: 1-3 vs Tottenham (A)
  

Manchester City are in a strong position as they aim to secure a top-four finish. Pep Guardiola's side are slowly returning to something close to their best as they look to put together a strong run of form, with the Champions League places looking very achievable after a disappointing campaign.

Last 5 league matches:

• Win: 1-0 vs Wolves (H)
• Win: 2-1 vs Aston Villa (H)
• Win: 2-0 vs Everton (A)
• Win: 5-2 vs Crystal Palace (H)
• Draw: 0-0 vs Man United (A)
  

Historically, Manchester City has dominated this fixture, with a strong record against Southampton. City have won 23 of the 39 Premier League matches played between the two sides, including the last three, with Southampton securing just seven victories.

• Man City 1-0 Southampton (26 Oct 2024)
• Southampton 1-4 Man City (08 Apr 2023)
• Man City 4-0 Southampton (08 Oct 2022)
• Southampton 1-1 Man City (22 Jan 2022)
• Man City 0-0 Southampton (18 Sep 2021)
  

• Charlie Taylor (Knock) - Doubt
• Ryan Fraser (Knock) - Doubt
  

• Nathan Ake (Foot) - Out
• Rodri (Knee) - Out
• John Stones (Thigh) - Doubt
  

Ramsdale; Stephens, Bednarek, Harwood-Bellis; Walker-Peters, Ugochukwu, Downes, Manning; Sulemana, Fernandes; Stewart

Ederson; Nunes, Dias, Gvardiol, O'Reilly; Bernardo, Kovacic; Marmoush, De Bruyne, Doku; Haaland

• Kevin De Bruyne vs Southampton's midfield: De Bruyne's creativity and vision will be crucial for City, and how Southampton's midfield copes with his influence could determine the game's flow.
• Erling Haaland vs Southampton's defence: If Haaland is fit to play, his presence up front will be a significant threat to Southampton's backline, which has struggled to keep clean sheets.
• Kamaldeen Sulemana vs Man City's full-backs: Sulemana's pace and dribbling ability could pose problems for City's defence.
  

Manchester City haven't lost a Premier League game at St. Mary's since July 2020.

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Odds and market details are accurate as of the time of publication.