Tottenham Hotspur vs Manchester United: Predictions, Betting odds, Lineups, Preview

Explore Ladbrokes' detailed preview for Tottenham Hotspur vs Manchester United in the Premier League. Stats, odds, predictions, and lineups for the 12:30 GMT match.

• Fixture: Tottenham Hotspur vs Manchester United

• Date: Saturday, 08 November 2025

• Kick-off: 12:30 GMT

• Venue: Tottenham Hotspur Stadium

Tottenham's up and down form could make this a tricky one. They've shown they can nick a win away from home, like against Everton and Leeds, but their home form's been dodgy lately. If they can keep it tight at the back like they did for spells against Chelsea, they might just frustrate United. But they'll need to be sharp up top to take their chances.

Manchester United have been on a decent run, bar that blip against Brentford. They've got the firepower to hurt Tottenham, especially after that 4-2 thrashing of Brighton. But that draw against Forest shows they can be caught napping. If they start strong and keep the pressure on, they could come away with the points.

Tottenham's recent form's been a bit of a rollercoaster. They've managed to pull off some solid away wins, but at home it's been a different story. That loss to Chelsea and the draw with Wolves show they can struggle to break down teams on their own turf. If they can find that away form at home, they might just surprise United.

Recent Premier League Results:

• Loss: 0-1 vs Chelsea (H)

• Win: 3-0 vs Everton (A)

• Loss: 1-2 vs Aston Villa (H)

• Win: 2-1 vs Leeds United (A)

• Draw: 1-1 vs Wolverhampton Wanderers (H)

United have been in pretty good nick lately, with only that loss to Brentford to worry about. They've shown they can score goals, especially at home, like against Brighton. But that draw at Forest suggests they need to be on it from the off. If they can keep up that intensity, they should fancy their chances against Tottenham.

Recent Premier League Results:

• Draw: 2-2 vs Nottingham Forest (A)

• Win: 4-2 vs Brighton & Hove Albion (H)

• Win: 2-1 vs Liverpool (A)

• Win: 2-0 vs Sunderland (H)

• Loss: 1-3 vs Brentford (A)

Tottenham have had the upper hand in recent meetings, winning three of the last five. They've managed to keep clean sheets in their last two games against United. But United have drawn twice against Tottenham in this five-game period, showing they can get a result against them. It's set to be a tight affair, with both teams knowing they can come out on top.

Recent Premier League Results

• Tottenham Hotspur 1-0 Manchester United (16 Feb 2025)

• Manchester United 0-3 Tottenham Hotspur (29 Sep 2024)

• Manchester United 2-2 Tottenham Hotspur (14 Jan 2024)

• Tottenham Hotspur 2-0 Manchester United (19 Aug 2023)

• Tottenham Hotspur 2-2 Manchester United (27 Apr 2023)

• Archie Gray (Muscle) - Out

• Ben Davies (Muscle) - Out

• James Maddison (Knee) - Out

• Radu Drăgușin (Knee) - Out

• Kota Takai (Foot) - Doubt

• Dominic Solanke (Ankle) - Doubt

• Yves Bissouma (Knee) - Doubt

• Dane Scarlett (Groin) - Doubt

• Dejan Kulusevski (Knee) - Doubt

• Lisandro Martínez (Knee) - Out

• Predicted lineup: Vicario (GK), Porro (DF), Danso (DF), Van de Ven (DF), Spence (DF), Palhinha (MF), Bentancur (MF), Kudus (MF), Sarr (MF), Bergvall (MF), Muani (AT)

With a solid backline and creative midfielders like Kudus and Bentancur, Tottenham will look to control the game and hit United on the break. Muani up top will be key to their attacking threat.

• Predicted lineup: Lammens (GK), Shaw (DF), de Ligt (DF), Yoro (DF), Diallo (MF), Casemiro (MF), Fernandes (MF), Dalot (MF), Mbeumo (MF), Cunha (MF), Šeško (AT)

United's attacking trio of Cunha, Mbeumo, and Šeško will look to exploit Tottenham's defence, while Fernandes and Casemiro will be crucial in dictating the tempo of the game.

• Lucas Bergvall vs Lenny Yoro: This will be a key battle between Tottenham's sharp attacker and United's young but capable defender.

• Pape Matar Sarr vs Bruno Fernandes: A fascinating midfield duel awaits between Tottenham's creative force and United's playmaker.

• Mohammed Kudus (Tottenham Hotspur): His ability to control the midfield and contribute to attacks will be vital for Tottenham.

• Bryan Mbeumo (Manchester United): Mbeumo's pace and finishing could be the difference for United in what may well be a close match.

Tottenham Hotspur vs Manchester United at 12:30 GMT on Saturday, 08 November 2025 is being broadcast live for viewers in the UK on TNT Sports 1 and TNT Sports Ultimate

Ladbrokes is predicting that the score will be Tottenham Hotspur 1-2 Manchester United

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