Premier League Gameweek 12 preview: Predictions & Odds

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Gameweek 12 Premier League preview

After the final international break of 2025, the Premier League is back this weekend. Gameweek 12 features several high-profile matches, and Ladbrokes previews them all.

The fixtures kick off at 12:30 GMT on Saturday, with Burnley hosting Chelsea at Turf Moor, aiming to make it difficult for the Champions League side on their own patch.

The highlight of the 15:00 GMT games sees Liverpool host Nottingham Forest at Anfield, aiming to get back to winning ways after a rather rough start to the season.

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The action doesn't stop there, as Saturday's 17:30 kick-off sees Manchester City travel to Newcastle, hoping to show that their 3-0 thrashing of Liverpool two weeks prior wasn't a fluke.

Things continue on Sunday with Arsenal hosting Tottenham in the first North London Derby of the season, while Old Trafford plays host to the final game of the gameweek, with Everton travelling to Manchester to play Man United.

Premier League Gameweek 12 Preview

Burnley vs Chelsea

Burnley may be one of the favourites for relegation, but they remain incredibly hard to play against, particularly when at home. Chelsea are likely to feel the brunt of that, which is why Ladbrokes is predicting a narrow win for Enzo Maresca's side.

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Bournemouth vs West Ham

They may be coming off the back of two consecutive losses in the Premier League, but Ladbrokes' team of experts still think that Bournemouth have enough to beat a West Ham side who, to their credit, have looked better under Nuno Espirito Santo.

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Brighton vs Brentford

A battle of the B's in the Premier League on Saturday afternoon as Brighton host Brentford at the AMEX. Ladbrokes is tipping a win for the home side, but only by a one-goal margin, so this really could go either way.

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Fulham vs Sunderland

Despite Sunderland's great start to life in the Premier League, including a recent 2-2 draw with Arsenal, Ladbrokes is tipping them to walk away with nothing when they face Fulham at Craven Cottage on Saturday.

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Liverpool vs Nottingham Forest

Liverpool have only lost once in the Premier League at Anfield so far this season, which explains why Ladbrokes is tipping them to beat Nottingham Forest at Anfield on Saturday afternoon.

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Wolves vs Crystal Palace

Rob Edwards' first match in charge of Wolves takes place on Saturday against Crystal Palace, and we're predicting the reigning FA Cup champions to get the better of the ex-Middlesbrough boss.

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Newcastle vs Man City

Eddie Howe is under pressure at Newcastle right now, and things aren't expected to get better for him this weekend. Our team of experts is predicting a win for Pep Guardiola and co.

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Leeds vs Aston Villa

Aston Villa have won just shy of 50% of their Premier League games this season, including a victory against Manchester City. Ladbrokes predicts a win once again for Unai Emery's side, this time away to Leeds.

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Arsenal vs Tottenham

They may be without several key names, including star man Gabriel, but Ladbrokes still expects Arsenal to have enough to beat their North London rivals at the Emirates in the first derby of the season.

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Man United vs Everton

Man United have 18 points from their opening 11 games, and we expect them to make it 21 from 12 come the end of Gameweek 12. The Red Devils are tipped to beat Everton at Old Trafford on Monday evening.

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Premier League Gameweek 12 Ten-Fold Preview

Ladbrokes has a five-fold Premier League accumulator already posted ahead of Gameweek 12, but for those interested in combining predictions from every single English top-flight game this weekend, you can do so below.

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How can I watch the 2025/26 Premier League season?

The Premier League 2025/26 season will be shown on Sky Sports and TNT Sports for viewers in the UK.

Can I bet on the Premier League?

Ladbrokes is offering a range of different betting markets on the Premier League, with Arsenal the current favourites to win the title.

Check out the latest betting promotions from Ladbrokes to enhance your betting experience.

For the best Premier League outright predictions, explore our Premier League Outright Betting guide.

All odds and market details are accurate as of the time of publication.

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