Following the release of the 2025/26 Premier League fixture schedule, Ladbrokes looks at when the biggest games are taking place next season.
Whether it's a clash between title challengers or a battle between two sides fighting against relegation, the release of the forthcoming season's fixtures always results in heaps of chatter amongst fans.
There's a lot of information to take in, so Ladbrokes has made it easy, looking at when the big six play against each other, and noting when the biggest derbies take place.
When the biggest Premier League 2025/26 games are taking place?
Liverpool set for early Newcastle, Everton and Arsenal ties
Liverpool are set for a big season, with the arrivals of Jeremie Frimpong, Milos Kerkez and Florian Wirtz set to aid Arne Slot's chances of retaining the Premier League title.
Within the first month of the season, Liverpool have to travel to St James' Park to play Newcastle, before hosting title rivals Arsenal at Anfield the following week.
It's a game against Everton at Anfield on September 20, with the first-ever Merseyside derby at Hill Dickinson Stadium taking place on April 18, 2026.
Below is a list of all of the 'big games' that fans need to be looking out for during the forthcoming season, with derbies and clashes between title rivals being highly-anticipated.
The 2024/25 Premier League season was officially won by Liverpool on April 27 after a 5-1 win over Tottenham. Arne Slot's side were crowned Champions with four games to spare.
Who are the favourites to win the 2025/26 Premier League?
The outright Premier League 2025/26 winner odds have Liverpool as the favourites to retain their crown, ahead of Arsenal and Manchester City in the betting.
Can you bet on next season's Premier League?
Ladbrokes is already giving customers the ability to bet on the winner of the 2025/26 Premier League, with Liverpool considered the favourite in that race by the bookies.
