Liverpool vs Manchester United: Predictions, Betting odds, Lineups, Preview

Explore Ladbrokes' detailed preview for Liverpool vs Manchester United in the Premier League. Stats, odds, predictions, and lineups for the 16:30 BST match.

• Fixture: Liverpool vs Manchester United

• Date: Sunday, 19 October 2025

• Kick-off: 16:30 BST

• Venue: Anfield

Match Prediction: Liverpool 2-1 Manchester United.

Liverpool's recent form has been a bit of a rollercoaster, with two losses on the road but solid wins at home. They'll be looking to use their home advantage again, pressing high and trying to exploit United's shaky away form. Manchester United, on the other hand, have been inconsistent, with a mix of wins and losses. They'll need to be more solid defensively if they want to leave Anfield with anything, but their attack could cause problems for Liverpool's backline.

Liverpool's recent results show they're strong at home but struggle away. Their last two home games were tight wins, which suggests they can grind out results when needed. However, those away losses to Chelsea and Crystal Palace might make them a bit nervous. They'll need to be sharp from the start and keep the pressure on United.

Recent Premier League Results:

• Loss: 1-2 vs Chelsea (A)

• Loss: 1-2 vs Crystal Palace (A)

• Win: 2-1 vs Everton (H)

• Win: 1-0 vs Burnley (A)

• Win: 1-0 vs Arsenal (H)

Manchester United's form has been up and down, with a convincing win against Sunderland but a heavy loss to Manchester City. Their away form is particularly concerning, losing to Brentford and City. They'll need to be more disciplined and focused if they want to get a result at Anfield. Their attack has shown it can score, but the defence needs to step up.

Recent Premier League Results:

• Win: 2-0 vs Sunderland (H)
• Loss: 1-3 vs Brentford (A)
• Win: 2-1 vs Chelsea (H)
• Loss: 0-3 vs Manchester City (A)
• Win: 3-2 vs Burnley (H)

The head-to-head record between Liverpool and Manchester United has been competitive recently, with three draws in their last five meetings. However, Liverpool's 7-0 thrashing of United in March 2023 shows they can dominate when everything clicks. The most recent encounter ended in a 2-2 draw, suggesting another close contest could be on the cards.

• Liverpool 2-2 Manchester United (05 Jan 2025)

• Manchester United 0-3 Liverpool (01 Sep 2024)

• Manchester United 2-2 Liverpool (07 Apr 2024)

• Liverpool 0-0 Manchester United (17 Dec 2023)

• Liverpool 7-0 Manchester United (05 Mar 2023)

• Alisson (Hamstring) - Out

• Giovanni Leoni (Cruciate Ligament) - Out

• Stefan Bajcetic (Hamstring) - Doubt

• Ibrahima Konaté (Muscle) - Doubt

• Wataru Endo (Knock) – Doubt

• Lisandro Martínez (Cruciate Ligament) - Out

• Tyrell Malacia (Lack of Fitness) - Doubt

• Noussair Mazraoui (Knock) - Doubt

• Predicted lineup: Mamardashvili, Bradley, Konaté (if fit), van Dijk, Kerkez, Gravenberch, Mac Allister, Salah, Szoboszlai, Gakpo, Isak

With a strong midfield trio of Szoboszlai, Mac Allister, and Gravenberch, Liverpool will look to control the game and press high up the pitch. Salah and Isak up front will be crucial in providing width and creating chances.

• Predicted lineup: Lammens, Yoro, de Ligt, Shaw, Diallo, Casemiro, Fernandes, Dalot, Mbeumo, Mount, Sesko

Manchester United's predicted lineup suggests they'll rely on Fernandes and Casemiro to control the midfield. Up front, Sesko and Mbeumo will need to be clinical if they want to break down Liverpool's defence.

• Alexander Isak vs Matthijs de Ligt: This will be a key battle between Liverpool's prolific frontman and Manchester United's solid defender.

• Alexis Mac Allister vs Casemiro: The midfield duel between Liverpool's energetic Mac Allister and Manchester United's experienced Casemiro will be crucial.

• Conor Bradley (Liverpool): Bradley's pace and directness on the wing could be a game-changer for Liverpool.

• Luke Shaw (Manchester United): Shaw's versatility and ability to contribute both defensively and offensively make him a key player for United.

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Odds and market details are accurate as of the time of publication.