Southampton vs Preston: Predictions, Betting odds, Lineups, Preview

Explore Ladbrokes' detailed preview for Southampton vs Preston in the Championship. Stats, odds, predictions, and lineups for the 15:00 BST match.

• Fixture: Southampton vs Preston
• Date: Saturday, 01 November 2025
• Kick-off: 15:00 BST
• Venue: St. Mary's Stadium

Southampton's recent form has been a bit of a rollercoaster, but they've shown they can nick a win away from home. They'll be looking to use that as a springboard against Preston. With attackers like Armstrong and Archer, they've got the firepower to cause problems. It's all about finding that consistency and capitalising on home advantage.

Preston, on the other hand, have had mixed results but can be dangerous on their day. Their win against Sheffield Utd shows they can compete with the best. They'll need to be solid at the back and clinical up top if they want to get something from this game. It could be a tight affair, but Southampton might just have the edge.

Southampton's recent form has been up and down, with two losses, two draws, and a win in their last five games. The losses to Blackburn and Bristol City away from home will be a concern, but they managed to grind out a win against Sheffield Utd on the road. At home, they've been solid, drawing against Swansea and Derby. They'll need to use that home form to their advantage and get back to winning ways.

• Loss: 1-2 vs Blackburn (A)
• Loss: 1-3 vs Bristol City (A)
• Draw: 0-0 vs Swansea (H)
• Draw: 1-1 vs Derby (A)
• Win: 2-1 vs Sheffield Utd (A)

Preston have had a mixed bag of results lately, with two wins, two losses, and a draw in their last five games. Their home form has been particularly inconsistent, losing to Birmingham and beating Sheffield Utd. On the road, they've managed a win against Charlton and a draw against Hull City. They'll need to be at their best to get a result against Southampton, especially away from home.

• Win: 3-2 vs Sheffield Utd (H)
• Loss: 0-1 vs Birmingham (H)
• Loss: 1-2 vs West Brom (A)
• Win: 2-0 vs Charlton (H)
• Draw: 2-2 vs Hull City (A)

Southampton have had the upper hand in recent meetings with Preston, winning their last encounter 3-0 and drawing 2-2 in the previous match. Their only other recent clash was a 2-1 win for Southampton in the League Cup back in 2011. This suggests Southampton might have the psychological edge going into this game.

• Southampton 3-0 Preston (16 Apr 2024)
• Preston 2-2 Southampton (25 Oct 2023)
• Southampton 2-1 Preston (21 Sep 2011) - League Cup

• Wellington (Suspended) - Out

• E. Jelert (Hip Injury) - Out

• S. Charles (Hamstring Injury) - Out

• F. Downes (Illness) - Doubt

• T. Fellows (Illness) - Doubt

• C. Jander (Illness) - Doubt

• C. Archer (Knock) - Doubt

• R. Stewart (Hamstring Injury) - Doubt

• Samuel Edozie (Hamstring Injury) - Doubt

• J. Thompson (Ankle Injury) - Out

• B. Potts (Muscle Injury) - Out

• R. Brady (Calf Injury) - Out

• W. Keane (Muscle Injury) - Out

• L. Gibson (Muscle Injury) - Doubt

• P. Valentin (Hamstring Injury) - Doubt

• Predicted lineup: McCarthy (GK), Edwards (DF), Wood (DF), Quarshie (DF), Roerslev (DF), Manning (DF), Azaz (MF), Bragg (MF), Armstrong (AT), Archer (if fit) (AT), Scienza (AT)

With a strong defensive line and attacking options like Armstrong and Archer, Southampton will look to control the game and exploit any gaps in Preston's defence. Their recent form suggests they need to be more clinical in front of goal to secure the win.

• Predicted lineup: Iversen (GK), Storey (DF), Gibson (DF), Hughes (DF), Offiah (MF), Armstrong (MF), Whiteman (MF), Devine (MF), Vukčević (MF), Jebbison (AT), Dobbin (AT)

Preston's lineup shows a balanced approach, with a solid backline and creative midfielders like Vukčević and Whiteman. They'll need to be disciplined and take their chances if they want to upset Southampton on their home turf.

• Archer vs Hughes: This will be a key battle between Southampton's sharp attacker and Preston's experienced defender.

• Azaz vs Whiteman: Southampton's midfielder Azaz will look to outmanoeuvre Preston's Whiteman in the middle of the park.

• Armstrong (Southampton): Armstrong's goal-scoring prowess makes him a vital player for Southampton, capable of turning the game in their favour.

• Vukčević (Preston): Vukčević's creativity in midfield could be crucial for Preston, providing the spark they need to break down Southampton's defence.

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Odds and market details are accurate as of the time of publication.