Newcastle vs Man United: Premier League preview, predictions and bet builder tips

• Ladbrokes previews Newcastle vs Man United in the Premier League

• Man United are in the mix for Champions League qualification, whilst Newcastle are fighting to finish inside the top ten.

• Ladbrokes predicts an away win for Man United, with Michael Carrick's side unbeaten in 2026.

Check out Ladbrokes' odds, in-depth preview, predictions and bet builder tips for Newcastle vs Man United ahead of their Premier League clash at St James' Park.

Man United have been the Premier League's form team this year, with their last loss coming on December 21, 2025. Our team of experts are tipping them to win once again this week, this time against Newcastle.

The Geordies have been having a much worse go of things than United in the Premier League. Eddie Howe's Newcastle have only won three of their last nine domestic league games, with losses to the likes of Liverpool and Man City.

• Fixture: Newcastle vs Man United

• Date: Wednesday, March 4, 2026

• Kick-off: 20:15 GMT

• Venue: St James' Park

Our prediction: Newcastle 1-2 Man United

Newcastle

Our predicted XI (4-3-3): Pope / Trippier, Thiaw, Botman, Hall / Willock, Tonali, Joelinton / Gordon, Barnes, Wissa

Man United

Our predicted XI (4-2-3-1): Lammens / Dalot, Yoro, Maguire, Mazraoui / Casemiro, Mainoo / Mbeumo, Fernandes, Cunha / Sesko

Man United to win

Man United are in great form right now, with Michael Carrick only failing to win one of his first seven Premier League matches in charge, a 1-1 draw against West Ham.

Whilst Newcastle away is one of the tougher matches a team can play in a season, the Geordies are without several key players, either due to injury or illness.

Due to Man United's good form, Newcastle's injuries and the poor performances that Eddie Howe's side come into this game off the back of, we're tipping the Red Devils to win once again this week.

Both teams to score in Newcastle vs Man United

Man United may be undefeated in the Premier League in 2026, but their defence has only kept clean sheets in three of their nine Premier League outings this year.

Recent wins over Crystal Palace, Arsenal and Fulham have seen Man United concede, so don't be surprised to see Newcastle put at least one past Senne Lammens on Wednesday evening.

Newcastle have also scored in losses to the likes of Liverpool and Man City this year, so even when playing and losing against top sides, Howe's men do often manage to find the back of the net.

So, the second leg of our Newcastle vs Man United bet builder features a tip of both teams to score.

Benjamin Sesko to have one shot on target

Despite initially struggling, Benjamin Sesko is proving to be the difference maker for Man United in the Premier League this year, with the former RB Leipzig man scoring the winner against Crystal Palace at the weekend.

Sesko has played nine Premier League matches this year, and scored six goals, with three of those coming in his last three games. It's clear that the striker is in a rich vein of form at the moment.

We aren't predicting him to find the back of the net, but we are tipping Sesko to test Newcastle's goalkeeper with a shot on target, something he's doing 1.2 times per game this season.

Bruno Fernandes to have two shots

For the final leg of our Newcastle vs Man United bet builder, we're tipping Bruno Fernandes to have two or more shots on Wednesday evening.

Bruno played in a deeper role under Ruben Amorim, but has shown fans that he remains one of the best 10s in the world since moving further forward this year under Michael Carrick.

Fernandes is getting shots off at a high rate too, averaging five shots every two Premier League games this season. In fact, in his side's game on Sunday against Palace, Bruno had four shots.

We're tipping Bruno to have two shots or more this week too, with this leg having come in in 50% of his matches so far in 2026.

You can bet on each of these markets individually, or combine them to create a Newcastle vs Man United Bet Builder, currently priced at just under 5/1.

With Bet Builder+, you can combine your bet with selections not only with other Premier League matches, but also with different sports.

View the latest football odds here.

All odds and markets are correct as of the date of publication.