2025/26 Premier League accumulator, betting tips & predictions

• Arsenal backed to beat rivals Spurs and claim the bragging rights in the North London Derby

• Manchester City tipped to get the better of Newcastle for the third time this season

• Wins predicted for Liverpool and Manchester United in their quests for the top four

Ladbrokes shares its Premier League 2025/26 weekly acca and betting tips, featuring Spurs vs Arsenal, plus Man City vs Newcastle and Liverpool's trip to Nottingham Forest.

A blockbuster round of Premier League action awaits, and our team of experts have put together a carefully considered four-fold accumulator, looking at form, stats, and live betting markets to guide our decisions.

So without further ado, let's dive into our weekly 2025/26 Premier League acca, with expert betting tips, odds and predictions.

Manchester City and Newcastle meet for the fourth (and remarkably not final) time this season when they face off at the Etihad on Saturday night, and despite the Magpies' recent upturn in form seeing them win three on the bounce, we're predicting a comfortable home win for Pep Guardiola's title chasers.

City's hopes of winning a fifth title in six years were given a huge boost on Wednesday as Arsenal collapsed at Wolves, and considering Newcastle haven't taken a single point from the Etihad since 2006, the hosts are firm favourites to pick up all three points here. Their odds of winning the league were slashed following Wednesday's shock result at Molineux, and with six wins from seven in all comps, City are really hitting their stride.

We're predicting a relatively comfortable home win here, with Newcastle failing to build on their excellent Champions League result in midweek.

Liverpool became the first Premier League team to win an away game at the Stadium of Light last week, giving their top four hopes a huge boost in the process, and we're predicting another enjoyable day out for the champions when they travel to Nottingham Forest on Sunday.

Four wins in five across all competitions have lifted spirits around Anfield after a stuttering start to 2026, and with Forest fighting to stave off the bottom three, Liverpool come into this as favourites - but it won't be straightforward. Nottingham Forest won 3-0 at Anfield back in November, and will also have the famous 'new manager bounce' following the arrival of Vitor Pereira, so we're expecting a lively atmosphere at the City Ground for Liverpool to contest with - but they should still have enough.

The Reds are in form, and with the attacking quality at Arne Slot's disposal, we're backing Liverpool to get the job done.

The game of the weekend comes from the Tottenham Hotspur Stadium as Spurs host Arsenal in the second North London Derby of the season, and with a real point to prove, we're tipping the Gunners to edge a tight affair.

The stage is set for a Premier League classic on Sunday afternoon, as Igor Tudor takes charge of his first game as Spurs boss against a bruised Arsenal side who are in danger of succumbing to the pressure. Wednesday's draw at Molineux was a disaster for Mikel Arteta's side, but the Gunners have no choice but to bounce back here if they want to keep the title race in their hands. Recent history suggests they'll have little problem navigating past Spurs, but this one will really test their title credentials.

We are backing the league leaders to scrape past their rivals in the North London Derby, maintaining their position at the top, but Arsenal will have to be at their best.

Rounding off our 2025/26 Premier League acca is the Monday-night clash between Everton and Manchester United, with the Red Devils tipped to get back to winning ways and resume their push for the Champions League places.

Both teams come into this one off the back of disappointing results, with Everton losing at home to Bournemouth and Man United drawing at West Ham, but strong form before that makes this an intriguing match at the Hill Dickinson Stadium. Everton won the reverse fixture at Old Trafford despite having 10 men for the best part of 80 minutes, but with Michael Carrick still unbeaten as United boss, we think the visitors will have too much quality.

Every point is crucial for Man United now as they look to finish inside the top four, and with Everton's season in danger of fading away, we're backing the visitors.

You can bet on these four games individually, or combine the matches into an accumulator bet.

As always, ensure you check the latest odds before confirming your bet, and remember to gamble responsibly. Good luck with your weekend bets!

If you're a fan of our Premier League predictions and betting tips, be sure to check out more Premier League betting content, including our take on the title odds.

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All odds and market details are accurate as of the time of publication.

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