Explore our detailed preview for Real Madrid vs Atletico Madrid in the Champions League Round of 16. Stats, predictions, and lineups for the 20:00 GMT match.

Real Madrid and Atlético Madrid meet in the Champions League knockout stage in what promises to be another fiercely contested derby. With Madrid boasting an elite home record in Europe and Atlético’s defensive resilience under Simeone, this tie is set to be a tactical chess match with a place in the quarter-finals on the line.
Real Madrid are unbeaten in their last three meetings against Atlético, but Atlético have won in European competition before (2018 UEFA Super Cup, 4-2). Will Madrid’s firepower secure a first-leg advantage, or can Atlético’s counter-attacking strategy deliver another surprise?
Match Prediction: Real Madrid 2-1 Aston Villa
Across all domestic competitions, these rivals have met 228 times, with Real Madrid winning 111, Atlético winning 56, and 61 ending in draws.
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Real Madrid (4-3-3)
Atlético Madrid (4-4-2)
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This promises to be another intense Madrid Derby, with Real Madrid aiming to take a first-leg lead before the return fixture at the Metropolitano. Expect a tactical battle, moments of brilliance, and Champions League drama at its finest.
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All odds and markets are correct as of the date of publication.