NFL RedZone Week 7 betting tips: Sunday, October 25, 2026

Atlanta Falcons vs San Francisco 49ers

San Francisco look like the most complete team in football at a perfect 6-0 to start the season, with quarterback Brock Purdy the early MVP frontrunner. Atlanta have dropped two in a row to fall to 2-4, and although Bijan Robinson is one of the best running backs in the league, the 49ers have one of the best in all-time in Christian McCaffrey. We're backing the new Super Bowl favourites to continue their unbeaten start.

Pick: 49ers money line

Minnesota Vikings vs Indianapolis Colts

Alongside the 49ers, the two remaining undefeated teams are the Vikings and the Chiefs. It hasn't been entirely convincing on offense for Minnesota, but their Brian Flores-led defense has been the best in the league and continues to flummox quarterbacks. It's a good matchup for them against Colts QB Daniel Jones, who's looked rusty coming off an achilles injury and thrown six interceptions this year. That included two last week in a loss to the previously winless Titans, so we're with the Vikings to cover the spread here.

Pick: Vikings -5.5

Detroit Lions vs Green Bay Packers

This should be a cracking game in the NFC North, one of two divisions (with the AFC North) where all the teams have a winning record this season. Detroit's offensive juggernaut, led by Jahmyr Gibbs and Amon-Ra St Brown, should be well rested coming off a bye, but their defense leaves plenty to be desired. The Lions have scored the joint-most points per game (32.8) but allowed the third-most against them (29.6). Packers QB Jordan Love should find joy throwing to Christian Watson and Matthew Golden, who are both averaging over 80 receiving yards per game. All five of Detroit's games this year have gone over the points total, and we think it'll happen again.

Pick: Over 52.5 points

Las Vegas Raiders vs Los Angeles Rams

It's officially time to panic for the Rams as they suffered a shocking upset - as 13.5-point favourites - last week to the Cardinals to fall to 2-4. The much-hyped preseason overwhelming Super Bowl favourites have stuttered out the blocks and are in real danger of missing the playoffs entirely. To make things worse, Davante Adams will miss up to two months and Puka Nacua could also be out this weekend. The Raiders have fought hard this season in close losses to the Chiefs and Bills, and we fancy them to cover the spread as underdogs at home.

Pick: Raiders +4.5

View the latest NFL odds.

All odds and markets are correct as of the date of publication.