Benfica vs Napoli: Predictions, Betting odds, Lineups, Preview

Explore Ladbrokes' detailed preview for Benfica vs Napoli in the UEFA Champions League. Stats, odds, predictions, and lineups for the 20:00 GMT match.

• Fixture: Benfica vs Napoli
• Date: Wednesday, 10 December 2025
• Kick-off: 20:00 GMT
• Venue: Estádio do Sport Lisboa e Benfica

Benfica's recent form has been a bit of a rollercoaster, with a strong win against Ajax but a string of losses before that. They'll be looking to bounce back at home, and with their predicted 4-2-3-1 lineup, they've got the firepower up top with Pavlidis leading the line. However, their defence will need to be on top form to keep Napoli's attackers at bay, especially with key players like Barreiro pulling the strings in midfield.

Napoli, on the other hand, have had a mixed bag of results, with a convincing win against Qarabag but a heavy defeat to PSV Eindhoven. Their 3-4-2-1 formation could cause problems for Benfica, with Neres and Lang supporting Højlund up front. If Napoli can exploit the spaces left by Benfica's attacking approach, they could come away with a positive result. But it's likely to be a close contest given both teams' recent performances.

Benfica's recent form has been a bit up and down, with a strong 2-0 win away at Ajax being the highlight. However, they've suffered four consecutive losses before that, including a 2-3 home defeat to Qarabag. This inconsistency might affect their confidence going into this match, but the win against Ajax could give them a much-needed boost.

Recent UEFA Champions League Results:

• Win: 2-0 vs Ajax (A)
• Loss: 0-1 vs Bayer Leverkusen (H)
• Loss: 0-3 vs Newcastle (A)
• Loss: 0-1 vs Chelsea (A)
• Loss: 2-3 vs Qarabag (H)

Napoli have had a mixed run of results lately, with a solid 2-0 home win against Qarabag and a 2-1 victory over Sporting CP. However, they've also had a heavy 2-6 loss to PSV Eindhoven and a 0-2 defeat to Manchester City. This inconsistency might make them unpredictable, but their recent wins could give them the momentum needed to perform well against Benfica.

Recent UEFA Champions League Results:

• Win: 2-0 vs Qarabag (H)
• Draw: 0-0 vs Eintracht Frankfurt (H)
• Loss: 2-6 vs PSV Eindhoven (A)
• Win: 2-1 vs Sporting CP (H)
• Loss: 0-2 vs Manchester City (A)

The head-to-head record between Benfica and Napoli shows two previous encounters, with Napoli coming out on top in both. In their most recent meeting, Napoli won 2-1 away at Benfica, while the earlier match saw Napoli triumph 4-2 at home. This suggests that Napoli have had the upper hand in recent clashes, which could give them a psychological edge going into this game.

Recent UEFA Champions League Results

• Benfica 1-2 Napoli (06 Dec 2016)
• Napoli 4-2 Benfica (28 Sep 2016)

• Dodi Lukebakio (Ankle) - Out

• Alexander Bah (Knee) - Doubt

• Bruma (Achilles) - Doubt

• Lendro Santos (Unknown) - Doubt

• Alex Meret (Foot) - Out

• Billy Gilmour (Groin) - Out

• Zambo Anguissa (Muscle) - Out

• Kevin De Bruyne (Thigh) - Out

• Miguel Gutierrez (Calf) - Doubt

• Romelu Lukaku (Thigh) - Doubt

• Predicted lineup: Trubin (GK), Dedic (DF), Otamendi (DF), Silva (DF), Dahl (DF), Rios (MF), Barrenechea (MF), Aursnes (MF), Barreiro (MF), Sudakov (MF), Pavlidis (AT)

Benfica are expected to line up in a 4-2-3-1 formation, with Trubin in goal and a back four of Dedic, Silva, Otamendi, and Dahl. In midfield, Rios and Barrenechea will provide the defensive cover, allowing Aursnes, Barreiro, and Sudakov to push forward and support striker Pavlidis.

• Predicted lineup: Milinkovic-Savic (GK), Rrahmani (DF), Buongiorno (DF), Beukema (DF), Di Lorenzo (MF), Lobotka (MF), McTominay (MF), Olivera (MF), Neres (MF), Lang (MF), Højlund (AT)

Napoli are likely to use a 3-4-2-1 formation, with Milinkovic-Savic between the sticks and a back three of Beukema, Rrahmani, and Buongiorno. The midfield quartet of Di Lorenzo, Lobotka, McTominay, and Olivera will look to control the game, while Neres and Lang will support Højlund up front.

• Vangelis Pavlidis vs Amir Rrahmani: Pavlidis will need to use his pace and movement to get past the experienced Rrahmani.

• Fredrik Aursnes vs Scott McTominay: Aursnes will have to outmanoeuvre McTominay in midfield to dictate the tempo of the game.

• Leandro Barreiro (Benfica): Barreiro's creativity and vision in midfield will be crucial for Benfica's attacking play.

• David Neres (Napoli): Neres' ability to create chances and link up with Højlund could be the key to Napoli's success.

Benfica vs Napoli at 20:00 GMT on Wednesday, 10 December 2025 is being broadcast live for viewers in the UK on TNT Sports 6

Ladbrokes is predicting that the score will be Benfica 1-2 Napoli in this match

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