Explore Ladbrokes' detailed preview for Napoli vs Qarabag in the UEFA Champions League. Stats, odds, predictions, and lineups for the 20:00 GMT match.

Napoli's recent form has been a bit of a rollercoaster, with a draw against Eintracht Frankfurt and a heavy loss to PSV Eindhoven. They'll be looking to bounce back with a strong performance at home, where they've shown they can win, as seen in their victory over Sporting CP. Expect Napoli to come out with a high press and try to dominate possession, leveraging their midfield strength to control the game's tempo.
Qarabag, on the other hand, have had some impressive results, including a draw against Chelsea and a win over Benfica. They've shown they can compete with top teams, but their away form has been less consistent. Qarabag might sit back and look to hit Napoli on the counter, using their pace and flair in attack to exploit any gaps in Napoli's defense. It should be a tight, tactical battle.
Napoli's recent form has been mixed, with a draw against Eintracht Frankfurt and a heavy defeat to PSV Eindhoven. However, they did manage a win against Sporting CP at home, which could give them confidence going into this match.
The loss to Manchester City away shows they can struggle against top teams, but at home, they might be able to turn things around. Napoli will need to be more clinical in front of goal and tighter at the back to secure a win against Qarabag.
Recent UEFA Champions League Results:
Draw: 0-0 vs Eintracht Frankfurt (H)
Loss: 2-6 vs PSV Eindhoven (A)
Win: 2-1 vs Sporting CP (H)
Loss: 0-2 vs Manchester City (A)
Qarabag have shown they can hold their own against strong opposition, drawing with Chelsea and beating Benfica. Their away form has been less convincing, with a loss to Athletic Club, but they've also managed a win against Benfica on the road.
Qarabag will need to be disciplined and organised if they want to get a result against Napoli. Their ability to score against top teams could be crucial in this match.
Recent UEFA Champions League Results:
Draw: 2-2 vs Chelsea (H)
Loss: 1-3 vs Athletic Club (A)
Win: 2-0 vs FC Copenhagen (H)
Win: 3-2 vs Benfica (A)
Loss: 2-3 vs Ferencvarosi TC (H)
These two teams have never met in European competition, so it's impossible to predict how these teams might fare against each other based on past encounters, which adds an element of unpredictability to the fixture. Both teams will be eager to set the tone in this new rivalry.
Alex Meret (Foot) - Out
Kevin De Bruyne (Thigh) - Out
Romelu Lukaku (Thigh) - Out
Billy Gilmour (Muscle) - Out
André-Frank Zambo Anguissa (Muscle) - Out
Leonardo Spinazzola (Muscle) - Doubt
No reported injuries or suspensions.
Predicted lineup: Milinkovic-Savic (GK), Di Lorenzo (DF), Rrahmani (DF), Buongiorno (DF), Gutierrez (DF), Elmas (MF), Lobotka (MF), McTominay (MF), Politano (AF), Hojlund (AT), Lang (AT)
Napoli's predicted lineup suggests a focus on midfield control with Lobotka and McTominay, aiming to dictate the game's pace and create scoring opportunities for Hojlund. The backline, led by Rrahmani and Buongiorno, will need to be solid to counter Qarabag's attacking threats.
Predicted lineup: Kochalski (GK), Silva (DF), Mustafazada (DF), Medina (DF), Cafarquliyev (DF), Bicalho (MF), Jankovic (MF), Borges (MF), Andrade (MF), Zoubir (MF), Duran (AT)
Qarabag's lineup indicates a balanced approach, with Jankovic and Bicalho providing stability in midfield, while Andrade and Zoubir will look to exploit spaces in Napoli's defence. The defence, anchored by Medina and Mustafazada, will need to be vigilant against Napoli's attacking prowess.
Napoli vs Qarabag at 20:00 GMT on Tuesday, 25 November 2025, will be broadcast live on TNT Sports 6 for viewers in the UK.
Ladbrokes is predicting that the score will be Napoli 2-1 Qarabag.
Ladbrokes is giving fans the ability to bet on various markets for Napoli vs Qarabag, including match betting, correct score and anytime scorer odds.
Ladbrokes brings you the most exciting offers to enhance your experience.
For the best UEFA Champions League outright predictions, explore our guide.
Odds and market details are accurate as of the time of publication.