Atletico Madrid vs Inter: Predictions, Betting odds, Lineups, Preview

Atletico Madrid's recent form shows they're a force to be reckoned with at home, smashing Union St. Gilloise and Eintracht Frankfurt. However, their away form has been dismal, with heavy defeats to Arsenal and Liverpool. This inconsistency might make them a bit unpredictable, but playing at home could give them the confidence boost they need to perform well against Inter.

Recent UEFA Champions League Results:

• Win: 3-1 vs Union St. Gilloise (H)
• Loss: 0-4 vs Arsenal (A)
• Win: 5-1 vs Eintracht Frankfurt (H)
• Loss: 2-3 vs Liverpool (A)

Inter have been on fire lately, winning all their recent matches with a strong defensive record. They've shown they can dominate both at home and away, which bodes well for their chances against Atletico Madrid. Their solid form and tactical discipline could be key in neutralising Atletico's attacking threats and securing a positive result.

Recent UEFA Champions League Results:

• Win: 2-1 vs Kairat Almaty (H)
• Win: 4-0 vs Union St. Gilloise (A)
• Win: 3-0 vs Slavia Praha (H)
• Win: 2-0 vs Ajax (A)

The head-to-head record between Atletico Madrid and Inter shows a closely contested rivalry. Inter have won the last two encounters, including a 1-0 victory in February 2024 and a 0-1 win in the International Champions Cup in 2018. However, Atletico Madrid managed to edge out Inter in a penalty shootout after a goalless draw in March 2024, suggesting that matches between these two teams are often tight and unpredictable.

Recent Results

• Atletico Madrid 0-0 (a.e.t.) (3-2 pen.) Inter (13 Mar 2024)

• Inter 1-0 Atletico Madrid (20 Feb 2024)

• Atletico Madrid 0-1 Inter (11 Aug 2018) - International Champions Cup

• Robin Le Normand (Knee) - Out

• Johnny Cardoso (Virus) - Doubt

• Julian Alvarez (Discomfort) - Doubt

• Jan Oblak (Muscle) - Doubt

• Ilias Kostis (Cruciate Ligament) - Doubt

• Henrikh Mkhitaryan (Thigh) - Doubt

• Matteo Darmian (Muscle) - Doubt

• Raffaele Di Gennaro (Hand) - Doubt

• Denzel Dumfries (Muscle) - Doubt

• Predicted lineup: Oblak (GK) (If fit), Llorente (DF), Gimenez (DF), Hancko (DF), Ruggeri (DF), Simeone (MF), Barrios (MF), Koke (MF), Baena (MF), Griezmann (AT), Alvarez (AT)(If fit)

With Le Normand out injured, Atletico Madrid will need to adapt their defensive strategy, relying on Hancko and Gimenez to shore up the backline. Their attacking trio of Baena, Griezmann, and Alvarez will be crucial in breaking down Inter's solid defence.

• Predicted lineup: Sommer (GK), Akanji (DF), Acerbi (DF), Bastoni (DF), Dumfries (MF)(If fit), Frattesi (MF), Barella (MF), Zielinski (MF), Dimarco (MF), Bonny (AT), Martinez (AT)

Inter's 3-5-2 formation should allow them to control the midfield with Barella, Frattesi, and Zielinski, while Akanji and Acerbi provide a solid defensive foundation. Bonny and Martinez up front will look to exploit any gaps in Atletico's defence on the counter-attack.

• Griezmann vs Acerbi: This will be a key battle between Atletico's creative forward and Inter's experienced defender.

• Barrios vs Barella: A midfield duel to watch, with Barrios looking to disrupt Inter's rhythm against Barella's creative play.

• Koke (Atletico Madrid): Koke's experience and leadership in midfield will be vital for Atletico Madrid's control and tempo.

• Bonny (Inter): Bonny's pace and finishing ability make him a dangerous threat up front.

Atletico Madrid vs Inter at 20:00 GMT on Wednesday, 26 November 2025, will be broadcast live for viewers in the UK on TNT Sports 6.

Ladbrokes is predicting that the score will be Atletico Madrid 1-1 Inter.

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For the best UEFA Champions League outright predictions, explore our guide.

Odds and market details are accurate as of the time of publication.